My child was diagnosed with intermittent lichen planus (white patch) on his tongue after starting rifaximin. Can rifaximin cause lichen planus?

Although lichen planus is associated with other inflammatory conditions, there is no reported association with the use of rifaximin. I have observed that the reversal of bacterial overgrowth (SIBO) by rifaximin seems to improve immune function. The improved immune function might make lichen planus more visually apparent, but this should not be confused with being the actual cause of lichen planus.nAs you may be aware, lichen planus can sometimes become cancerous, so regular examinations by an oral surgeon are strongly recommended.

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